Food in.
Energy out.
B vitamins are how your body turns food into fuel. ZETA B-Complete gives you all eight — with folate, B2, B6 and B12 already in their active forms, ready to work.
“The key methylated B-vitamins are critical because they are more bioavailable, meaning the body’s ability to use the supplement completely. From their extensive antioxidant effects, to their impact on maintaining healthy homocysteine levels, optimized B-vitamin levels sustain healthy hearts, blood cells and neurologic function.”
B vitamin support
A steady routine
Take as directed.
Individual response varies.
Discuss whether testing blood panels to check your B-levels is appropriate.
Ongoing nutrition and energy support.
The B story
Eight B’s. One team.
B vitamins help turn food into energy. This formula includes active forms to support how your body uses them.
Folate · B9
Methylfolate is an active form of folate. Quatrefolic® supplies it as a glucosamine salt.
Thiamine · B1
A fat-soluble derivative of thiamine, included alongside thiamine HCl.
Vitamin B6
The active coenzyme form of vitamin B6, which supports normal nervous system function.*
Vitamin B12
An active form of B12 that supports normal red blood cell formation and nervous system function.*
All eight B’s. Zero noise.
Other ingredients: Capsule (hypromellose and water), stearic acid, magnesium stearate, silica.
Quatrefolic® is a registered trademark of Gnosis S.p.A. Produced under U.S. Patent 7,947,662.
- Take 1 capsule once or twice a day — or as directed by your healthcare professional.
- Best timing: the morning. B’s are part of your energy system — give them the day to work.
- Every day matters more than timing. Your body doesn’t store most B’s, so steady wins.
Riboflavin note
Riboflavin (B2) can make urine appear bright yellow. Contact a healthcare professional about unexplained changes or other symptoms.
Real results
What people say
For the Curious
B vitamins, ingredients, directions, and the research behind this formula.
Description
ZETA B-Complete provides full spectrum B vitamins, including activated B2, B6, and B12, alongside benfotiamine and Quatrefolic®. B vitamins support carbohydrate metabolism, healthy nervous system, adrenal and immune function, cardiovascular health, and mental function and mood.*
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Ingredients
Thiamin (as thiamine HCl) 20 mg (1667% DV); Riboflavin (as riboflavin 5′-phosphate sodium) 20 mg (1538% DV); Niacin (as niacinamide and niacin) 140 mg (875% DV); Vitamin B6 (as pyridoxal 5′-phosphate) 20 mg (1176% DV); Folate (as (6S)-5-methyltetrahydrofolic acid, glucosamine salt) 680 mcg DFE (170% DV); Vitamin B12 (as methylcobalamin) 400 mcg (16667% DV); Biotin 400 mcg (1333% DV); Pantothenic Acid (as d-calcium pantothenate) 150 mg (3000% DV); Choline (as choline dihydrogen citrate) 30 mg (5% DV); Benfotiamine 20 mg (Daily Value not established).
Other ingredients: Capsule (hypromellose and water), stearic acid, magnesium stearate, silica.
Why methylfolate
Folate is provided as 5-methyltetrahydrofolate (5-MTHF), which bypasses metabolic steps to folate bioactivity. Research shows large doses of folic acid can "force" its conversion to the active form, but 5-MTHF may be the preferred form to replenish folate — especially for people with digestive challenges or genetic variations in folate metabolism (such as MTHFR). Red blood cell folate has been shown to be higher after supplementation with 5-MTHF compared to folic acid and placebo; in one pharmacokinetic study, 5 mg of 5-MTHF produced plasma 5-MTHF levels 700% greater than folic acid.*
Why benfotiamine
Benfotiamine (S-benzoylthiamine O-monophosphate) is a safe, fat-soluble analog of thiamine — the most potent of a class of thiamine compounds found in small amounts in the Allium family (garlic, onions). Its structure lets it diffuse easily through cell membranes, then become active inside. One study showed it raised blood and tissue thiamine at least five times higher than the water-soluble salt and remained bioavailable up to 3.6 times longer. Benfotiamine increases transketolase activity, helping steer glucose metabolism away from pathways that form advanced glycation end products (AGEs).*
Why P5P
Pyridoxal-5′-phosphate is the active coenzyme form of B6. In a study of patients with impaired liver function, only 33% of those given pyridoxine HCl showed a rise in plasma P5P — while every patient given P5P did.*
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Quatrefolic® is a registered trademark of Gnosis S.p.A. Produced under U.S. Patent 7,947,662.
Directions
Take one capsule either once or twice daily, or as directed by your healthcare professional. Consult your healthcare professional prior to use. Individuals taking medication should discuss potential interactions with their healthcare professional.
Research
The research underneath.
A few of the studies behind the forms in ZETA B-Complete:
Key study · Loew D. (1996). Pharmacokinetics of thiamine derivatives especially of benfotiamine. International Journal of Clinical Pharmacology and Therapeutics 34(2):47–50. PMID: 8929745.
Willems FF, Boers GH, Blom HJ et al. (2004). Pharmacokinetic study on utilisation of 5-methyltetrahydrofolate and folic acid in patients with coronary artery disease. British Journal of Pharmacology 141(5):825–30. PMID: 14769778.
Labadarios D, Rossouw JE, McConnell JB et al. (1977). Vitamin B6 deficiency in chronic liver disease—evidence for increased degradation of pyridoxal-5-phosphate. Gut 18:23–27. PMID: 838399.
Thornalley PJ. (2005). Potential role of thiamine (vitamin B1) in diabetic complications. Current Diabetes Reviews 1(3):287–98. PMID: 18220605.
Stirban A, Negrean M, Stratmann B et al. (2006). Benfotiamine prevents macro- and microvascular endothelial dysfunction and oxidative stress following meal rich in advanced glycation end products in individuals with type 2 diabetes. Diabetes Care 29(9):2064–71. PMID: 16936154.
Kluijtmans LA et al. (1996). Molecular genetic analysis in mild hyperhomocysteinemia: common mutation in methylenetetrahydrofolate reductase gene. American Journal of Human Genetics 58(1):35–41. PMID: 8554066.
Woelk H, Lehrl S, Bitsch R et al. (1998). Benfotiamine in treatment of alcoholic polyneuropathy: 8-week randomized controlled study (BAP I Study). Alcohol and Alcoholism 33(6):631–38. PMID: 9872352.
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